good vibrations, BM mesenchymal stem cell senescence, hematopoiesis - brief notes

Yesterday Lifespan.io reported on a finding by Wen et al. (2021) that vibration at 90 Hz reduced cellular senescence in bone marrow mesenchymal stem cells; from the news article's conclusion:

https://www.lifespan.io/news/vibration-reduces-cellular-senescence-in-the-bones-of-rats/

"Further, while maintaining bone density is crucial to extending healthspan, vibration does not seem to be a great candidate as an anti-aging therapy. One of the greatest advantages of a longevity-based approach is its application to all the tissues in the body, and while the authors of this study did not investigate the effect of vibration on other organs, it seems logical that these effects would apply only to bone tissue."

 Original research article:

https://www.aging-us.com/article/202907/text

 However -

https://pubmed.ncbi.nlm.nih.gov/16364518/

“Longstanding evidence that bone formation and resorption are required for the development of haemopoietic marrow strongly suggests that osteoblasts play a crucial role in haemopoiesis and recent evidence indicates that they area key element of the haemopoietic niche.”

So I should think that this could impact more than bone density. There’s also the effect of osteocalcin on the brain to consider.

Additionally, vibration feeds back to motor control neural pathways and affects brain oscillations – see research on ‘vibrotactile coordinated reset’ for Parkinson’s disease. Vibrotactile stimulation also has effects on the autonomic nervous systems and is used to treat anxiety (e.g., Apollo Neuro, Doppel).

 

 

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