Video Notes: Mast Cell Activation Syndrome - Making the Difficult Diagnosis with Dr. Tania Dempsey
Mast Cell Activation Syndrome - Making the Difficult Diagnosis with Dr. Tania Dempsey (interviewed by Dr Michell, channel - The Smartest Doctor in the Room) uploaded 19 May 2022 18:00 breast implants & other surgical implants, dental implants as MCAS triggers 20:45 diagnostic testing for MCAS 21:38 blood markers - histamine, chromogranin A, tryptase, heparin 22:39 24-hour urine metabolites - N-methylhistamine, prostaglandin D2, leukotrienes, 2,3-Dinor-11beta-prostaglandin F2 alpha 23:01 CD117 marker staining of tissue biopsy samples (endoscopy or colonoscopy) ; mast cell count 26:00 eosinophilic esophagitis, comparison w/ recognition of disease; many EoE pts have MCAS {comment: it's my understanding that mast cells recruit eosinophils} 28:17 Bartonella, need to treat underlying causes of MCAS 29:24 vitamin D receptors on mast cells 30:12 problem of excipients in medications and supplements 31:08 improvement in neurologic symptoms