The Rhyothemis princeps Brain Externalization Project

A recent flare up of fibrocystic breast symptoms had me wondering if use of cold packs has any effect on breast cancer (BC) risk. Cold packs are often recommended for mastalgia (breast pain) from fibrocystic breast disease, mastitis, engorgement due to breast feeding cessation, and post breast cancer surgery. Whole body cold exposure has been found to increase tumor growth and metastasis in mice: https://www.medicalnewstoday.com/articles/269266 T-cell function is diminished at colder temperature leading to reduced anti-tumor immune responses. The article notes implications for standard research practice of housing mice at relatively colder temperatures - another thing to add to the list of problems in current practices.  (Could cold acclimation be used to promote tolerance in autoimmunity and atopy? Another topic for another day.) The mice were subjected to whole body cold exposure  - not spot treatment. It is conceivable that reducing acute inflammation through localized cold exposure

 There are a number of research programs that study interventions for increasing lifespan and healthspan in animals (dogs, mice, flies, nematode worms) with the aim of finding successful interventions that could be translated to humans. The Dog Aging Project enrolls companion dogs in observational and interventional studies on aging; it seems a worthwhile endeavor even if treatments are not applicable to humans as improving the lifespan and healthspan of dogs is worthwhile for its own sake. To date, however, there has not been a similar project for cats - or has there?  I watch a lot of cat videos and came upon one that reported ultra-longevity in a number of cats apparently achieved through diet and lifestyle interventions implemented by their human companion, Jake Perry. It seems strange that I learned about this from a cat video rather than through all the longevity-related media I consume. https://youtu.be/CXGCJeH4e-w?t=32   An article by Christina Couch published in Atlas Obscura

Marine collagen peptides have antioxidant properties.  Characterization and Antioxidant Activity of Collagen, Gelatin, and the Derived Peptides from Yellowfin Tuna (Thunnus albacares) Skin [2020] - https://pubmed.ncbi.nlm.nih.gov/32023998/  Functional and bioactive properties of collagen and gelatin from alternative sources: A review [2011] - https://www.sciencedirect.com/science/article/pii/S0268005X11000427 "The exact mechanism underlying the antioxidant activity of peptides is not fully understood, but various studies have shown that they are lipid peroxidation inhibitors, free radical scavengers and transition metal ion chelators. According to some studies, gelatin peptides could inhibit lipid peroxidation more efficiently than antioxidative peptides derived from many other protein sources ...   .. peptides isolated from hoki skin gelatin were capable of enhancing the expression of antioxidative enzymes such as glutathione peroxidase, catalase and superoxide dismutas