Nocturia, Aquaporins, and Oxytocin
[2020-7-13] Someone posted about nocturia on HealthUnlocked's Parkinson's Movement forum and I replied with the following (I don't think I can keep up with doing the reference properly, perhaps if it starts to really bother me I will edit): Apart from prostate and autonomic nervous system problems, one issue in aging related to nocturia might be loss of function of aquaporins. Aquaporins are membrane channels for water; though water can diffuse across cell membranes AQPs move water faster and are particularly important under stress conditions. AQP function declines with age and could contribute to many age-related health issues including reduction in blood brain barrier function. hindawi.com/journals/omcl/2... ncbi.nlm.nih.gov/pmc/articl... Oxytocin has some vassopressin-like activity and helps move AQP from inside the cell to the membrane surface when needed. jasn.asnjournals.org/conten... Oxytocin levels decline with age: ncbi.nlm.nih.gov/pmc/articl... The probiot