Procalcitonin and other biomarkers in COVID-19
[2020-07-01] Procalcitonin in Emergency Department Patients With Suspected COVID-19 Presentation by Dr. Charles Cairns On using biomarkers (classifiers) to distinguish between causes of acute inflammation (infectious vs non infectious, bacterial vs viral, co-infections) with emphasis on procalcitonin. Procalcitonin is elevated in severe covid, but not in non-severe (95% of cases) 5:37 inflammatory response over the time course of infection / injury recovery 12:15 sepsis survivors vs. sepsis non-survivors gene expression profile shows marked difference 16:54 procalcitonin (PCT) is a prohormone of calcitonin ; elevated PCT levels indicate bacterial infection accompanied by systemic inflammatory reaction 24:28 nice diagram of events in SARS-CoV-2 infection 25:09 another really nice diagram { seems to indicate that antibody dependent enhancement can occur in the course of a single infection, rather than during a re-infection } 29:11 laboratory parameters in covid-19 pat