Na/K ATPase - thermogenesis & energetic cost
There's this book I want to get, Hochachka and Somero's Biochemical Adaptation (or the latest edition, which is by Somero et al.); of course since it is a science book it is ridiculously expensive and there's no ILL in a pandemic. The book has some interesting passages (p. 402) on Na/K ATPase that are visible on Google Books preview. I took a snip since there's no cut and paste: Main points: - futile cycling of ions may play a vital role in thermogenesis - Na/K ATPase may account for 5-10% of BMR - there are differences in Na/K ATPase activity between ectotherms and endotherms - 7x higher activity in mammals - "Correlated with this difference in estimated costs of sodium pump activity were differences in in the rates if passive efflux of K+ and passive influx of Na+ in liver cells. The costs of maintaining transmembrane gradients in concentrations of Na+ and K+ are reflected in differences in sodium pump-dependent oxygen consumption." - the degree of differen