Cereblon & Lon protease
From a discussion with OS on MedCram (which had gone way OT from sex differences relating to covid-19 pathology - link to discussion thread ): re: AMPK bat genetics - not much yet, but there's this one Positive Selection of Cereblon Modified Function Including Its E3 Ubiquitin Ligase Activity and Binding Efficiency With AMPK - https://pubmed.ncbi.nlm.nih.gov/30836149/ Note the same modification is present in both bats and rodents. Hamsters do seem to have some protection from oxidative stress, but they are not particularly long-lived as are bats. They are what's termed 'r selected' - with a life history characterized by high reproductive rate and short life-span. Here's an article that points out that oxidative stress defenses may be tissue specific and that hamsters may not have as much protection in the brain: Oxidative Damage Does Not Occur in Striped Hamsters Raising Natural and Experimentally Increased Litter Size - https://www.ncbi.