vomiting, metabolic acidosis, alkaline tide - brief notes

https://www.justintimemedicine.com/CurriculumContent/p/4954

"This basolateral secretion of HCO3− into the bloodstream is sometimes called the “alkaline tide” which normally accompanies gastric acid secretion with eating. The metabolic alkalosis of vomiting is essentially an exaggeration of this response; HCl is lost from the stomach so more is made to replace it, causing even more bicarb to be secreted "out the back end" of the parietal cell and into the bloodstream."

 

from Wikipedia:

"Alkaline tide refers to a condition, normally encountered after eating a meal, where during the production of hydrochloric acid by parietal cells in the stomach, the parietal cells secrete bicarbonate ions across their basolateral membranes and into the blood, causing a temporary increase in pH.[1]"

 

~

PPIs can cause metabolic acidosis; can be prescribed to prevent metabolic alkalosis from vomiting.

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